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ea0081oc4.2 | Oral Communications 4: Pituitary and Neuroendocrinology 1 | ECE2022

Measurements of growth hormone in neonatal screening cards as a non-invasive and feasible tool: reference values in healthy term newborns

Giacchetti Federico , Vidali Matteo , Sangiorgio Andrea , Rodari Giulia , Vantaggiato Chiara , Di Modugno Adriana , Morniroli Daniela , Colombo Lorenzo , Profka Eriselda , Dall'Antonia Alberta , Mosca Fabio , Ceriotti Ferruccio , Arosio Maura , Gianni' Maria Lorella , Giavoli Claudia

Background: Severe congenital growth hormone deficiency (cGHD) is a rare but potentially life-threatening condition. Even though random growth hormone (GH) can confirm cGHD during the first week of life, the diagnosis remains extremely challenging in the absence of reliable reference values in healthy neonates and thus of a best diagnostic cut-off.Aims: First, to provide solid reference values for GH concentrations in term newborns, by means of a non-inv...

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ea0090oc3.4 | Oral Communications 3: Pituitary and Neuroendocrinology 1 | ECE2023

Measurements of growth hormone using dried blood spots in preterm neonates: reference values and longitudinal evaluation.

Giacchetti Federico , Vidali Matteo , Orsenigo Chiara , Vizzari Giulia , Tarricone Silvia , Vantaggiato Chiara , Rodari Giulia , Modugno Adriana Di , Napolitano Filomena , Sangiorgio Andrea , Morniroli Daniela , Colombo Lorenzo , Profka Eriselda , Collini Valentina , Gianni Maria Lorella , Mantovani Giovanna , Mosca Fabio , Ceriotti Ferruccio , Arosio Maura , Giavoli Claudia

Background and Aim: Congenital growth hormone deficiency (cGHD) is a rare but life-threatening condition whose diagnosis is challenging in the absence of reliable reference values, both in healthy neonates and in preterm ones. We recently estimated GH reference interval in 1036 healthy, at-term newborns (HN) form dried blood spot samples using a previously validated analytical method. Aim of this study is to provide values for random GH in preterm newborns (PN).<p class="a...

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Endocrine Abstracts

Measurements of growth hormone in neonatal screening cards as a non-invasive and feasible tool: reference values in healthy term newborns

Measurements of growth hormone using dried blood spots in preterm neonates: reference values and longitudinal evaluation.

BiosciAbstracts